ZUC algorithm is developed in China by the Chinese academy of sciences and other units, in new generation broadband wireless mobile communication system international encryption standard. And at present, the algorithm is realized by software, and the efficiency and speed of the ZUC stream cipher algorithm needs to be improved. In order to adapt to the era of big data demand for highspeed realtime data encryption, and further promote the use of ZUC algorithm, considering about the feature of ZUC algorithm for efficient,we use hardware description language VHDL design FPGA hardware and integrated simulation using Xilinx ISE software company design is correct. Finally, it will be encapsulated into the IP soft core module. According to the design of ARM and FPGA platform for Xilinx company corresponding interface software for actual testing, performance analysis and resources assessment, for ZUC algorithm provides a highly efficient hardware design reference. Finally, we use the ZUC module in video data encryption. Compared with the pure software to realize the same function, the system performance improved nearly 3 times. It can satisfy the realtime video data encryption.