Taking 42HS03 stepping motor as the control and drive object, a highly reliable stepper motor subdivision driver system is designed based on dsPIC33F MCU. The system could set the stepper motor’s speed and position with the upper computer software. Lower machine calculate the current value of the motor and pulse width modulation (PWM) with looking up to the table. With respect to the existing mature stepper motor driver, this drive system is smaller and has a simpler structure, and the interface is simple, easy to operate. This paper introduces the system hardware circuit design and program flow. Results show that the experimental is consistent with theoretical analysis, and the system is stable.